Antimicrobial Resistance Patterns of Klebsiella pneumoniae Isolated from Clinical Samples at Al-Furat Hospital: A Cross-Sectional Study

Authors

  • noor nasser جامعة الفرات الأوسط التقنية Author
  • Athraa Nasser Abed Author
  • Mahmood M. Fahad Author

DOI:

https://doi.org/10.46649/x7rxyg24

Keywords:

Antimicrobial resistance (AMR), Clinical isolates, Klebsiella pneumonia , Multidrug resistance, Urinary and bloodstream infections

Abstract

Background: The alarming rise of antimicrobial resistance (AMR) particularly in Klebsiella pneumoniae is a significant concern to global health. To determine the antimicrobic resistance profile of K. pneumoniae collected from clinical specimens taken from Al-Furat Hospital and correlate them with the specimen types and classes of relevent antibiotics. Methods: A cross sectional study of 150 clinical specimens (urine, blood, sputum, stool) was conducted at Al-Furat Hospital, Kufa, Iraq from October 1, 2024 to January 2, 2025. Standard methods were employed for bacterial cultures and eight commonly used antibiotics were tested for microbial sensitivity. The statistical operations performed were descriptive analysis and chi-squared, The results were shown in bar graphs, heatmaps, and pie graphs. Results: 132 out of 150 specimens gave positive bacterial culture. The most frequently isolated organism was K pneumoniae (83.3%) and its resistance to ampicillin(81.8%) and ceftazidime (96.4%) was extremely high. Resistance was more marked in urine and blood isolates as highlighted in heat maps. Chi-square tests demonstrated there were relationships between specimen type and resistance levels for multiple antibiotics tested (p < 0.05). Conclusion: K. pneumoniae emerged as the most important resistant pathogen in the Kasturba Hospital, where resistance was found to vary significantly depending on the sample source. Empirical management and regular monitoring of resistance patterns should be instituted.

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Published

2025-07-15

Issue

Vol. 1 No. 2 (2025): Al-Furat Journal for Health and Medical Sciences

Section

Microbiology

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How to Cite

Antimicrobial Resistance Patterns of Klebsiella pneumoniae Isolated from Clinical Samples at Al-Furat Hospital: A Cross-Sectional Study. (2025). Al-Furat Journal for Health and Medical Sciences , 1(2), 90-99. https://doi.org/10.46649/x7rxyg24